Projects
Here are the projects I'm currently working on:
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a fatal, underdiagnosed, yet curable disease which afflicts the pulmonary arteries. We create a patient-specific model to help physicians choose the right lesions to treat for optimal prognosis.
Malignant CD8+ T cells cause cardiovascular impairment in mice - using mathematical models, can we find an optimal amount of T cells to preserve immune and cardiovascular function?
Pseudomonas aeruginosa is resistant to antibiotic treatment, leading scientists and physicians to propose using bacteriophages as treatment. However, since this method is so new, we propose mathematical models to learn more about phage therapy.
Esophageal Adenocarcinoma and Barrett's Esophagus
Esophageal cancer is the sixth leading cause of death in the US. Chemotherapy and radiotherapy are general therapies for cancer but come with many side effects. Instead, we explore the efficacy of IL-6 immunotherapy and find patient-specific dosing.
